Recombinant Mouse Dcps Protein, Myc/DDK-tagged
Cat.No. : | Dcps-2478M |
Product Overview : | Purified recombinant protein of mouse full-length decapping enzyme, scavenger (Dcps), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) to m7GMP. May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP. Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre-mRNAs. Inhibits activation-induced cell death. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 39 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Dcps decapping enzyme, scavenger [ Mus musculus (house mouse) ] |
Official Symbol : | Dcps |
Synonyms : | DCPS; decapping enzyme, scavenger; scavenger mRNA-decapping enzyme DcpS; DCS-1; HINT-5; mRNA decapping enzyme; histidine triad protein member 5; hint-related 7meGMP-directed hydrolase; AA408441; 1700001E16Rik |
Gene ID : | 69305 |
mRNA Refseq : | NM_027030 |
Protein Refseq : | NP_081306 |
UniProt ID : | Q9DAR7 |
Products Types
◆ Recombinant Protein | ||
DCPS-11864H | Recombinant Human DCPS protein(7-160 aa), His-tagged | +Inquiry |
DCPS-01R | Recombinant Rhesus monkey DCPS Protein, His-tagged | +Inquiry |
DCPS-11863H | Recombinant Human DCPS protein(7-160 aa), GST-tagged | +Inquiry |
DCPS-11862H | Recombinant Human DCPS protein(1-337 aa), His-tagged | +Inquiry |
DCPS-01C | Recombinant Cynomolgus monkey DCPS Protein, His-tagged | +Inquiry |
◆ Lysates | ||
DCPS-7046HCL | Recombinant Human DCPS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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