Recombinant Mouse Dnase2a Protein, Myc/DDK-tagged

• Cat.No.: Dnase2a-2616M
• Product Overview: Purified recombinant protein of mouse full-length deoxyribonuclease II alpha (Dnase2a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 39.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dnase2a deoxyribonuclease II alpha [ Mus musculus (house mouse) ]
• Official Symbol: Dnase2a
• Synonyms: Dnase2a; deoxyribonuclease II alpha; Dnase2; deoxyribonuclease-2-alpha; DNase II alpha; acid DNase; lysosomal DNase II; EC 3.1.22.1
• Gene ID: 13423
• mRNA Refseq: NM_010062
• Protein Refseq: NP_034192
• UniProt ID: P56542