Recombinant Mouse Dpf1 Protein, Myc/DDK-tagged
Cat.No. : | Dpf1-2633M |
Product Overview : | Purified recombinant protein of mouse full-length D4, zinc and double PHD fingers family 1 (Dpf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 44.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Dpf1 D4, zinc and double PHD fingers family 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Dpf1 |
Synonyms : | Dpf1; D4, zinc and double PHD fingers family 1; Neud; Neud4; neuro; zinc finger protein neuro-d4; BAF45B; BRG1-associated factor 45B; neuro-d4; neuronal d4 domain family member |
Gene ID : | 29861 |
mRNA Refseq : | NM_013874 |
Protein Refseq : | NP_038902 |
UniProt ID : | Q9QX66 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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