Recombinant Mouse Dsg2 protein, His-SUMO-tagged
Cat.No. : | Dsg2-2824M |
Product Overview : | Recombinant Mouse Dsg2 protein(O55111)(55-618aa), fused to N-terminal His tag and SUMO tag, was expressed in E. coli. |
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Source : | E. coli |
Species : | Mouse |
Tag : | His-SUMO |
Form : | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Molecular Mass : | 78.6 kDa |
Protein length : | 55-618aa |
AA Sequence : | AWITAPVALREGEDLSRKNPIAKIH SDLAEEKGIKITYKYTGKGITEPPF GIFVFDRNTGELNITSILDREETPY FLLTGYALDSRGNNLEKPLELRIKV LDINDNEPVFTQEVFVGSIEELSAA HTLVMKITATDADDPETLNAKVSYR IVSQEPANSHMFYLNKDTGEIYTTS FTLDREEHSSYSLTVEARDGNGQIT DKPVQQAQVQIRILDVNDNIPVVEN KMYEGTVEENQVNVEVMRIKVTDAD EVGSDNWLANFTFASGNEGGYFHIE TDTQTNEGIVTLVKEVDYEEMKKLD LSIIVTNKAAFHKSILSKYKATPIP ITVKVKNVVEGIHFKSSVVSFRASE AMDRSSLSRSIGNFQVFDEDTGQAA KVTYVKVQDTDNWVSVDSVTSEIKL VKIPDFESRYVQNGTYTAKVVAISK EHPQKTITGTIVITVEDVNDNCPVL VDSVRSVCEDEPYVNVTAEDLDGAQ NSAPFSFSIIDQPPGTAQKWKITHQ ESTSVLLQQSERKRGRSEIPFLISD SQGFSCPERQVLQLTVCECLKGGGC VAAQYDNYVGLGPA |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. |
Gene Name : | Dsg2 desmoglein 2 [ Mus musculus ] |
Official Symbol : | Dsg2 |
Synonyms : | DSG2; desmoglein 2; desmoglein-2; AA408168; D18Ertd293e; |
Gene ID : | 13511 |
mRNA Refseq : | NM_007883 |
Protein Refseq : | NP_031909 |
Products Types
◆ Recombinant Protein | ||
DSG2-2868H | Recombinant Human DSG2 protein(741-900 aa), C-His-tagged | +Inquiry |
Dsg2-56M | Recombinant Mouse Dsg2 Protein | +Inquiry |
DSG2-2540M | Recombinant Mouse DSG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
DSG2-400H | Recombinant Human DSG2 Protein, His-tagged | +Inquiry |
DSG2-4100H | Recombinant Human DSG2 protein(50-609aa), His-tagged | +Inquiry |
◆ Lysates | ||
DSG2-6807HCL | Recombinant Human DSG2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDesmoglein-2 plays a role in wound healing and tissue repair by facilitating cell adhesion and migration. Manipulating its activity may have therapeutic implications for enhancing these processes.
Desmoglein-2 expression is regulated at transcriptional and post-translational levels. Dysregulation is linked to autoimmune diseases like pemphigus, where autoantibodies target Desmoglein-2, leading to skin blistering.
Desmoglein-2 has a unique molecular structure with extracellular domains facilitating cell-cell adhesion. It interacts with other desmosomal components, such as Desmocollins and Plakoglobin, forming strong intercellular junctions.
Desmoglein-2 participates in cell signaling, impacting pathways involved in cell adhesion, migration, and survival. Its interactions with other desmosomal components modulate signaling cascades essential for cellular function.
Desmoglein-2 influences EMT, a process crucial for cancer invasion and metastasis. Changes in Desmoglein-2 expression and localization contribute to alterations in cell adhesion dynamics during EMT.
Customer Reviews (3)
Write a reviewUnmatched product superiority, professional customer service, and delivery that exceeded expectations.
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