| Description : |
Enables epidermal growth factor binding activity and epidermal growth factor-activated receptor activity. Involved in cellular response to amino acid stimulus and positive regulation of fibroblast proliferation. Acts upstream of or within several processes, including animal organ development; epidermal growth factor receptor signaling pathway; and protein autophosphorylation. Located in several cellular components, including basolateral plasma membrane; endocytic vesicle; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; integumental system; limb; and respiratory system. Used to study Coronavirus infectious disease and aortic valve disease. Human ortholog(s) of this gene implicated in several diseases, including colorectal cancer; lung non-small cell carcinoma (multiple); pancreatic cancer; prostate cancer; and pulmonary tuberculosis. Orthologous to human EGFR (epidermal growth factor receptor). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
70.1 kDa |
| Protein Length : |
1210 |
| AA Sequence : |
MRPSGTARTTLLVLLTALCAAGGAL EEKKVCQGTSNRLTQLGTFEDHFLS LQRMYNNCEVVLGNLEITYVQRNYD LSFLKTIQEVAGYVLIALNTVERIP LENLQIIRGNALYENTYALAILSNY GTNRTGLRELPMRNLQEILIGAVRF SNNPILCNMDTIQWRDIVQNVFMSN MSMDLQSHPSSCPKCDPSCPNGSCW GGGEENCQKLTKIICAQQCSHRCRG RSPSDCCHNQCAAGCTGPRESDCLV CQKFQDEATCKDTCPPLMLYNPTTY QMDVNPEGKYSFGATCVKKCPRNYV VTDHGSCVRACGPDYYEVEEDGIRK CKKCDGPCRKVCNGIGIGEFKDTLS INATNIKHFKYCTAISGDLHILPVA FKGDSFTRTPPLDPRELEILKTVKE ITGFLLIQAWPDNWTDLHAFENLEI IRGRTKQHGQFSLAVVGLNITSLGL RSLKEISDGDVIISGNRNLCYANTI NWKKLFGTPNQKTKIMNNRAEKDCK AVNHVCNPLCSSEGCWGPEPRDCVS CQNVSRGRECVEKCNILEGEPREFV ENSECIQCHPECLPQAMNITCTGRG PDNCIQCAHYIDGPHCVKTCPAGIM GENNTLVWKYADANNVCHLCHANCT YGCAGPGLQGCEVWPSGPKIPSIAT GIVGGLLFIVVVALGIGLFMRRRHI VRKRTLRRLLQERELVEPLTPSGEA PNQAHLRILKETEFKKIKVLGSGAF GTVYKGLWIPEGEKVKIPVAIKELR EATSPKANKEILDEAYVMASVDNPH VCRLLGICLTSTVQLITQLMPYGCL LDYVREHKDNIGSQYLLNWCVQIAK GMNYLEDRRLVHRDLAARNVLVKTP QHVKITDFGLAKLLGAEEKEYHAEG GKVPIKWMALESILHRIYTHQSDVW SYGVTVWELMTFGSKPYDGIPASDI SSILEKGERLPQPPICTIDVYMIMV KCWMIDADSRPKFRELILEFSKMAR DPQRYLVIQGDERMHLPSPTDSNFY RALMDEEDMEDVVDADEYLIPQQGF FNSPSTSRTPLLSSLSATSNNSTVA CINRNGSCRVKEDAFLQRYSSDPTG AVTEDNIDDAFLPVPEYVNQSVPKR PAGSVQNPVYHNQPLHPAPGRDLHY QNPHSNAVGNPEYLNTAQPTCLSSG FNSPALWIQKGSHQMSLDNPDYQQD FFPKETKPNGIFKGPTAENAEYLRV APPSSEFIGA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
