Recombinant Mouse Eps15 Protein, MYC/DDK-tagged
Cat.No. : | Eps15-965M |
Product Overview : | Purified recombinant protein of full-length mouse epidermal growth factor receptor pathway substrate 15 (Eps15), with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Plays a role in the assembly of clathrin-coated pits (CCPs). Acts as a clathrin adapter required for post-Golgi trafficking. Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 64.8 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Eps15 epidermal growth factor receptor pathway substrate 15 [ Mus musculus (house mouse) ] |
Official Symbol : | Eps15 |
Synonyms : | Eps15 epidermal; growth factor receptor pathway substrate 15; 2410112D09Rik; epidermal growth factor receptor substrate 15; epidermal growth factor pathway substrate 15; protein AF-1p |
Gene ID : | 13858 |
mRNA Refseq : | NM_001159964 |
Protein Refseq : | NP_001153436 |
UniProt ID : | P42567 |
Products Types
◆ Recombinant Protein | ||
EPS15-653H | Recombinant Human EPS15 protein(657-798aa), His-tagged | +Inquiry |
EPS15-2827M | Recombinant Mouse EPS15 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPS15-2939C | Recombinant Chicken EPS15 | +Inquiry |
EPS15-5265M | Recombinant Mouse EPS15 Protein | +Inquiry |
◆ Lysates | ||
EPS15-6578HCL | Recombinant Human EPS15 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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