Recombinant Mouse Eri1 Protein, Myc/DDK-tagged
Cat.No. : | Eri1-2859M |
Product Overview : | Purified recombinant protein of mouse full-length exoribonuclease 1 (Eri1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Binds with high affinity to the 3' side of the stem-loop structure and to the downstream cleavage product (DCP) of histone pre-mRNAs. Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 39.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Eri1 exoribonuclease 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Eri1 |
Synonyms : | ERI1; exoribonuclease 1; 3-5 exoribonuclease 1; eri-1 homolog; 3-5 exonuclease ERI1; enhanced RNAi protein 1; histone mRNA 3-exonuclease 1; three prime histone mRNA exonuclease 1; histone mRNA 3 end-specific exonuclease; Thex1; eri-1; 3hexo; 3110010F15Rik |
Gene ID : | 67276 |
mRNA Refseq : | NM_026067 |
Protein Refseq : | NP_080343 |
UniProt ID : | Q7TMF2 |
Products Types
◆ Recombinant Protein | ||
ERI1-2849M | Recombinant Mouse ERI1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERI1-1795R | Recombinant Rat ERI1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERI1-1251H | Recombinant Human ERI1 Protein, C-MYC/DDK-tagged | +Inquiry |
Eri1-7908M | Recombinant Mouse Eri1 protein, His & T7-tagged | +Inquiry |
ERI1-1590C | Recombinant Chicken ERI1 | +Inquiry |
◆ Lysates | ||
ERI1-6554HCL | Recombinant Human ERI1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket