Recombinant Mouse F13a1 protein, His & T7-tagged
Cat.No. : | F13a1-1499M |
Product Overview : | Recombinant Mouse F13a1 aa. (Asn372~Ser616 (Accession # Q8BH61)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes subunit A of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit B to form a heterotetrameric proenzyme that undergoes thrombin-mediated proteolysis to generate active factor XIIIa. The transglutaminase activity of factor XIIIa is required for the calcium-dependent crosslinking of fibrin, leading to the formation of a clot. Mice lacking the encoded protein display impaired reproduction and reduced survival due to bleeding episodes, hematothorax, hematoperitoneum and subcutaneous hemorrhage. Additionally, mice lacking the encoded protein exhibit impaired wound healing and inadequate healing of myocardial infarction. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Mouse |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 31.3kDa. |
Protein length : | Asn372~Ser616 (Accession # Q8BH61) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method). |
Purity : | >95% |
Characteristic : | The isoelectric point is 5.9. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | F13a1 coagulation factor XIII, A1 subunit [ Mus musculus (house mouse) ] |
Official Symbol : | F13a1 |
Synonyms : | F13a; AI462306; 1200014I03Rik; coagulation factor XIII, alpha subunit; coagulation factor XIIIa; protein-glutamine gamma-glutamyltransferase A chain; transglutaminase A chain; coagulation factor XIII A chain |
Gene ID : | 74145 |
mRNA Refseq : | NM_001166391.1 |
Protein Refseq : | NP_001159863.1 |
UniProt ID : | Q8BH61 |
Products Types
◆ Recombinant Protein | ||
F13A1-3609H | Recombinant Human F13A1 Protein, GST-tagged | +Inquiry |
F13a1-2900M | Recombinant Mouse F13a1 Protein, Myc/DDK-tagged | +Inquiry |
F13A1-1332H | Recombinant Human F13A1 Protein, His-tagged | +Inquiry |
F13A1-881H | Recombinant Human F13A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
F13A1-2497H | Recombinant Human F13A1 protein(431-520 aa), C-His-tagged | +Inquiry |
◆ Native Protein | ||
F13A1-1881H | Native Human Coagulation Factor XIII, A1 Polypeptide | +Inquiry |
F13A1-28806TH | Native Human F13A1 | +Inquiry |
F13A1-5399H | Native Human Coagulation Factor XIII, A1 Polypeptide | +Inquiry |
◆ Lysates | ||
F13A1-6485HCL | Recombinant Human F13A1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket