Recombinant Mouse F2rl1 Protein, His&GST-tagged

• Cat.No.: F2rl1-2178M
• Product Overview: Recombinant Mouse F2rl1 Protein (Val311-Tyr399) with a N-His&GST tag was expressed in E. coli.

Specification

• Description: Predicted to enable G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and G-protein beta-subunit binding activity. Involved in positive regulation of glomerular filtration. Acts upstream of or within with a positive effect on vasodilation. Predicted to be located in early endosome; plasma membrane; and pseudopodium. Predicted to be integral component of plasma membrane. Biomarker of lung disease. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and respiratory allergy. Orthologous to human F2RL1 (F2R like trypsin receptor 1).
• Source: E. coli
• Species: Mouse
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 40 kDa
  Accurate Molecular Mass: 42 kDa
• Protein length: Val311-Tyr399
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: F2rl1 F2R like trypsin receptor 1 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: F2rl1
• Synonyms: F2rl1; F2R like trypsin receptor 1; Par2; Par-2; proteinase-activated receptor 2
  Proteinase-activated receptor-2, G protein-coupled receptor 11
  coagulation factor II (thrombin) receptor-like 1
  coagulation factor II receptor-like 1
  thrombin receptor-like 1
• Gene ID: 116677
• mRNA Refseq: NM_053897
• Protein Refseq: NP_446349
• UniProt ID: Q63645