Recombinant Mouse Fabp5, His-tagged

• Cat.No.: Fabp5-255M
• Product Overview: Recombinant Mouse Fabp5, fused with hexahistidine-tagged at N-terminal, was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and participate in fatty acid uptake, transport, and metabolism. In humans this gene has been associated with psoriasis and type 2 diabetes. In mouse deficiency of this gene in combination with a deficiency in Fabp4 confers protection against atherosclerosis, diet-induced obesity, insulin resistance and experimental autoimmune encephalomyelitis (the mouse model for multiple sclerosis). Alternative splicing results in multiple transcript variants that encode different protein isoforms. The mouse genome contains many pseudogenes similar to this locus.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: A solution in 50 mM sodium phosphate, pH 7.2, containing 20% glycerol and 150 mM sodium chloride
• Molecular Mass: 19.3 kDa
• Purity: ≥95%
• Stability: 1 year
• Storage: -80°C
• Concentration: 0.5 mg/ml
• Shipping: Dry ice in continental US; may vary elsewhere

Gene Information

• Gene Name: Fabp5 fatty acid binding protein 5, epidermal [ Mus musculus (house mouse) ]
• Official Symbol: Fabp5
• Synonyms: Fabp5; Klbp; mal1; Fabpe; E-FABP; PA-FABP; fatty acid binding protein 5, epidermal; fatty acid-binding protein, epidermal; keratinocyte lipid-binding protein; epithelial fatty acid-binding protein; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog
• Gene ID: 16592
• mRNA Refseq: NM_001272097
• Protein Refseq: NP_001259026
• UniProt ID: Q05816
• Chromosome Location: 3 A1-A3; 3
• Pathway: PPAR signaling pathway
• Function: lipid binding; transporter activity

Reviews

06/12/2020

The product's rapid action in triggering cellular responses significantly expedited our experiments.

12/15/2018

Precise immunoprecipitation results consistently reflected the product's quality.

05/05/2016

Replicating outcomes across diverse cell lines underscored the product's consistent behavior.

Q&As

What diseases or conditions are associated with dysregulation or abnormal expression of FABP5?

Dysregulation or abnormal expression of FABP5 is associated with conditions such as cancer, metabolic disorders, and inflammatory diseases.

What is the primary function of Fatty Acid-Binding Protein 5 (FABP5) in cellular processes and lipid metabolism?

Fatty Acid-Binding Protein 5 (FABP5) functions in cellular processes, primarily playing a role in lipid metabolism and fatty acid transport.

How does FABP5 contribute to the regulation of lipid homeostasis and inflammatory responses in cells?

FABP5 contributes to the regulation of lipid homeostasis and inflammatory responses in cells, linking lipid metabolism to immune function.

Are there therapeutic implications or potential targets related to FABP5 in diseases involving lipid metabolism and inflammation?

There are potential therapeutic implications related to FABP5 in diseases involving lipid metabolism and inflammation, making it a target for drug development.

How does FABP5 participate in the binding and transport of fatty acids within cells?

FABP5 participates in the binding and transport of fatty acids within cells, facilitating their intracellular trafficking.

In which cellular compartments is FABP5 predominantly localized?

FABP5 is predominantly localized in the cytoplasm of cells, where it binds and transports fatty acids.

Are there specific types of fatty acids that FABP5 preferentially interacts with, influencing its cellular functions?

FABP5 preferentially interacts with long-chain fatty acids, influencing its cellular functions related to lipid metabolism.