Recombinant Mouse Fermt1 Protein, Myc/DDK-tagged

• Cat.No.: Fermt1-2987M
• Product Overview: Purified recombinant protein of mouse full-length fermitin family member 1 (Fermt1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 77.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fermt1 fermitin family member 1 [ Mus musculus (house mouse) ]
• Official Symbol: Fermt1
• Synonyms: FERMT1; fermitin family homolog 1 (Drosophila); fermitin family homolog 1; unc-112-related protein 1; Kindlin-1; 5830467P10Rik; RP23-308A23.1
• Gene ID: 241639
• mRNA Refseq: NM_198029
• Protein Refseq: NP_932146
• UniProt ID: P59113