Recombinant Mouse Fgd2 Protein, Myc/DDK-tagged

• Cat.No.: Fgd2-2991M
• Product Overview: Purified recombinant protein of mouse full-length FYVE, RhoGEF and PH domain containing 2 (cDNA clone MGC:30923 IMAGE:4016697), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 52.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fgd2 FYVE, RhoGEF and PH domain containing 2 [ Mus musculus (house mouse) ]
• Official Symbol: Fgd2
• Synonyms: Fgd2; FYVE, RhoGEF and PH domain containing 2; tcs; Tcd2; tcs-; tcs2; Tcd-2; tcs-2; ZFYVE4; FYVE, RhoGEF and PH domain-containing protein 2; Fgd1 family, member 2; Fgd2-like protein; faciogenital dysplasia homolog 2; faciogenital dysplasia protein 2; t-complex distorter 2
• Gene ID: 26382
• mRNA Refseq: NM_013710
• Protein Refseq: NP_038738
• UniProt ID: Q8BY35