Recombinant Mouse Foxe3 Protein, His-tagged

• Cat.No.: Foxe3-1517M
• Product Overview: Recombinant Mouse Foxe3 Protein (Asn110-Leu288) with N-His tag was expressed in E. coli.

Specification

• Description: Enables sequence-specific DNA binding activity. Involved in camera-type eye development; negative regulation of lens fiber cell differentiation; and positive regulation of lens epithelial cell proliferation. Acts upstream of or within camera-type eye development; cell development; and positive regulation of epithelial cell proliferation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; eye; and heart. Used to study congenital aphakia. Human ortholog(s) of this gene implicated in anterior segment dysgenesis; anterior segment dysgenesis 2; cataract 34 multiple types; and thoracic aortic aneurysm. Orthologous to human FOXE3 (forkhead box E3).
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 22.4 kDa
  Accurate Molecular Mass: 22 kDa
• Protein length: Asn110-Leu288
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Foxe3 forkhead box E3 [ Mus musculus (house mouse) ]
• Official Symbol: Foxe3
• Synonyms: FOXE3; forkhead box E3; forkhead box protein E3; dysgenetic lens; Rinshoken cataract; dyl; rct; FREAC8
• Gene ID: 30923
• mRNA Refseq: NM_015758
• Protein Refseq: NP_056573
• UniProt ID: Q9QY14