Recombinant Mouse Galc, Myc-His-tagged
Cat.No. : | Galc-200M |
Product Overview : | Recombinant Mouse Galactocerebrosidase/ GALC Protein,C-Myc & His Tag (Mouse Galactocerebrosidase /GALC ) Tyr 43 - Arg 684 (Accession # P54818) was produced in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Galactocerebrosidase (GALC) is also known as GALCERase, Galactocerebroside beta-galactosidase, Galactosylceramidase and Galactosylceramide beta-galactosidase, which belongs to the glycosyl hydrolase 59 family. Galactocerebrosidase / GALC hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. GALC with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. Defects in Galc are the cause of the "twitcher" phenotype. |
Source : | HEK293 |
Species : | Mouse |
Tag : | Myc-His |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM MES, pH 6.5 with 100 mM NaCl. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Endotoxin : | Less than 1.0 EU per μg of the Mouse Galactocerebrosidase /GALC by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). |
Reconstitution : | See Certificate of Analysis for reconstitution instructions and specific concentrations. |
Gene Name : | Galc galactosylceramidase [ Mus musculus ] |
Official Symbol : | Galc |
Synonyms : | GALC; galactosylceramidase; galactocerebrosidase; GALCERase; galactocerebroside beta-galactosidase; galactosylceramide beta-galactosidase; twi; Gacy; AW212969; AW413532; twitcher; 2310068B06Rik; A930008M05Rik; |
Gene ID : | 14420 |
mRNA Refseq : | NM_008079 |
Protein Refseq : | NP_032105 |
Pathway : | Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolic pathways, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem; Sphingolipid metabolism, conserved biosystem; |
Function : | catalytic activity; cation binding; galactosylceramidase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; |
Products Types
◆ Recombinant Protein | ||
GALC-528H | Recombinant Human GALC Protein, His-tagged | +Inquiry |
GALC-1624R | Recombinant Rhesus Macaque GALC Protein, His (Fc)-Avi-tagged | +Inquiry |
Galc-529R | Recombinant Rat Galc Protein, His-tagged | +Inquiry |
GALC-4676H | Recombinant Human GALC Protein, GST-tagged | +Inquiry |
GALC-1844H | Recombinant Human GALC Protein (43-685 aa), His-tagged | +Inquiry |
◆ Lysates | ||
GALC-679HCL | Recombinant Human GALC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket