Recombinant Mouse Gdnf Protein (Ser78-Ile211), C-His tagged, Animal-free, Carrier-free

• Cat.No.: Gdnf-30M
• Product Overview: Recombinant Mouse Gdnf Protein (Ser78-Ile211) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Glial Cell Line-derived Neurotrophic Factor (GDNF) is the neurotrophic factor, belonging to the GDNF family of ligands (GFL) and identifying as a therapeutic candidate in Parkinson's disease. GDNF is a 23.7 kDa protein containing 211 residues that plays a critical role in promoting the survival and differentiation of midbrain dopamine neurons. Besides, GDNF is revealed to facilitate the development of peripheral tissues such as kidney, pancreas and lung. Additionally, as a member of GFL, GDNF also takes part in the progression of tumor.
• Source: E. coli
• Species: Mouse
• Tag: C-His
• Form: Lyophilized
• Molecular Mass: The protein has a calculated MW of 15.91 kDa.
  The protein migrates about 17 kDa under reducing condition (SDS-PAGE analysis).
• Protein Length: Ser78-Ile211
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: Gdnf glial cell line derived neurotrophic factor [ Mus musculus (house mouse) ]
• Official Symbol: Gdnf
• Synonyms: GDNF; glial cell line derived neurotrophic factor; glial cell line-derived neurotrophic factor; ATF; mGDNF; neurotrophic factor; astrocyte-derived trophic factor; AI385739
• Gene ID: 14573
• mRNA Refseq: NM_010275
• Protein Refseq: NP_034405
• UniProt ID: P48540