Recombinant Mouse Glb1 Protein, MYC/DDK-tagged

• Cat.No.: Glb1-706M
• Product Overview: Purified recombinant protein of full-length mouse galactosidase, beta 1 (Glb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. The encoded protein is a lysosomal enzyme that catalyzes the hydrolysis of terminal beta-D-galactose residues in various substrates like lactose, ganglioside GM1 and other glycoproteins. Mutations in the human gene are associated with GM1-gangliosidosis and Morquio B syndrome. Disruption of the mouse gene mirrors the symptoms of human gangliosidosis. Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 73 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Glb1 galactosidase, beta 1 [ Mus musculus (house mouse) ]
• Official Symbol: Glb1
• Synonyms: Glb1; galactosidase, beta 1; Bge; Bgl; Bgs; Bgt; Bgl-e; Bgl-s; Bgl-t; AW125515; C130097A14Rik; beta-galactosidase; acid beta-galactosidase; lactase; EC 3.2.1.23
• Gene ID: 12091
• mRNA Refseq: NM_009752
• Protein Refseq: NP_033882
• UniProt ID: P23780