Recombinant Mouse Hace1 Protein, Myc/DDK-tagged
Cat.No. : | Hace1-3350M |
Product Overview : | Purified recombinant protein of mouse full-length HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (Hace1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 102.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Hace1 HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Hace1 |
Synonyms : | HACE1; HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1; E3 ubiquitin-protein ligase HACE1; HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1; BC025474; 1700042J16Rik; A730034A22Rik; KIAA1320 |
Gene ID : | 209462 |
mRNA Refseq : | NM_172473 |
Protein Refseq : | NP_766061 |
UniProt ID : | Q3U0D9 |
Products Types
◆ Recombinant Protein | ||
HACE1-1039H | Recombinant Human HACE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HACE1-0420H | Recombinant Human HACE1 Protein (E2-A909), Tag Free | +Inquiry |
HACE1-4049M | Recombinant Mouse HACE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HACE1-4552H | Recombinant Human HACE1 Protein, GST-tagged | +Inquiry |
HACE1-0421H | Recombinant Human HACE1 Protein (E2-A909), His tagged | +Inquiry |
◆ Lysates | ||
HACE1-5648HCL | Recombinant Human HACE1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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