Recombinant Mouse HAVCR2 Protein, Fc-tagged

• Cat.No.: HAVCR2-739M
• Product Overview: Recombinant Mouse HAVCR2 protein with Fc tag was expressed in HEK293.

Specification

• Description: Predicted to enable metal ion binding activity. Involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and toll-like receptor signaling pathway. Located in cell surface; early endosome; and immunological synapse. Is expressed in several structures, including dorsal aorta; gut; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2).
• Source: HEK293
• Species: Mouse
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: 45.8 kDa
• Protein Length: 281
• AA Sequence: MFSGLTLNCVLLLLQLLLARSLEDG YKVEVGKNAYLPCSYTLPTSGTLVP MCWGKGFCPWSQCTNELLRTDERNV TYQKSSRYQLKGDLNKGDVSLIIKN VTLDDHGTYCCRIQFPGLMNDKKLE LKLDIKAAKVTPAQTAHGDSTTASP RTLTTERNGSETQTLVTLHNNNGTK ISTWADEIKDSGETIRTAIHIGVGV SAGLTLALIIGVLILKWYSCKKKKL SSLSLITLANLPPGGLANAGAVRIR SEENIYTIEENVYEVENSNEYYCYV NSQQPS
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: Havcr2 hepatitis A virus cellular receptor 2 [ Mus musculus (house mouse) ]
• Official Symbol: HAVCR2
• Synonyms: HAVCR2; hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; TIMD-3; HAVcr-2; T-cell membrane protein 3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; Tim3; TIM-3; Timd3; MGC124149; MGC124150
• Gene ID: 171285
• mRNA Refseq: NM_134250
• Protein Refseq: NP_599011
• UniProt ID: Q8VIM0