Recombinant Mouse Hsd11b2 Protein, MYC/DDK-tagged

• Cat.No.: Hsd11b2-1176M
• Product Overview: Purified recombinant protein of full-length mouse hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 42.6 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 [ Mus musculus (house mouse) ]
• Official Symbol: Hsd11b2
• Synonyms: Hsd11b2; hydroxysteroid 11-beta dehydrogenase 2; 11HSD2; corticosteroid 11-beta-dehydrogenase isozyme 2; 11-DH2; 11-beta-HSD2; 11-beta-hydroxysteroid dehydrogenase type 2; NAD-dependent 11-beta-hydroxysteroid dehydrogenase; EC 1.1.1.146
• Gene ID: 15484
• mRNA Refseq: NM_008289
• Protein Refseq: NP_032315
• UniProt ID: P51661