Recombinant Mouse Insrr Protein, Myc/DDK-tagged

• Cat.No.: Insrr-3555M
• Product Overview: Purified recombinant protein of mouse full-length insulin receptor-related receptor (Insrr), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 145.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Insrr insulin receptor-related receptor [ Mus musculus (house mouse) ]
• Official Symbol: Insrr
• Synonyms: INSRR; insulin receptor-related receptor; insulin receptor-related protein; IR-related receptor; Irr
• Gene ID: 23920
• mRNA Refseq: NM_011832
• Protein Refseq: NP_035962
• UniProt ID: Q9WTL4