Recombinant Mouse IRF8 Protein (1-424 aa), His-SUMO-tagged
Cat.No. : | IRF8-586M |
Product Overview : | Recombinant Mouse IRF8 Protein (1-424 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
Description : | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune syst. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory elent, followed by cooperative binding of BATF and IRF8 and activation of genes. |
Source : | E. coli |
Species : | Mouse |
Tag : | His-SUMO |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 64.2 kDa |
Protein length : | 1-424 aa |
AA Sequence : | MCDRNGGRRLRQWLIEQIDSSMYPG LIWENDEKTMFRIPWKHAGKQDYNQ EVDASIFKAWAVFKGKFKEGDKAEP ATWKTRLRCALNKSPDFEEVTDRSQ LDISEPYKVYRIVPEEEQKCKLGVA PAGCMSEVPEMECGRSEIEELIKEP SVDEYMGMTKRSPSPPEACRSQILP DWWVQQPSAGLPLVTGYAAYDTHHS AFSQMVISFYYGGKLVGQATTTCLE GCRLSLSQPGLPKLYGPDGLEPVCF PTADTIPSERQRQVTRKLFGHLERG VLLHSNRKGVFVKRLCQGRVFCSGN AVVCKGRPNKLERDEVVQVFDTNQF IRELQQFYATQSRLPDSRVVLCFGE EFPDTVPLRSKLILVQVEQLYARQL VEEAGKSCGAGSLMPALEEPQPDQA FRMFPDICTSHQRPFFRENQQITV |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
Gene Name : | Irf8 interferon regulatory factor 8 [ Mus musculus ] |
Official Symbol : | IRF8 |
Synonyms : | IRF8; Myls; ICSBP; IRF-8; Icsbp1; AI893568; |
Gene ID : | 15900 |
mRNA Refseq : | NM_008320 |
Protein Refseq : | NP_032346 |
UniProt ID : | P23611 |
Products Types
◆ Recombinant Protein | ||
Irf8-1206M | Recombinant Mouse Irf8 Protein, MYC/DDK-tagged | +Inquiry |
IRF8-2122R | Recombinant Rhesus Macaque IRF8 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRF8-1201H | Recombinant Human IRF8 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRF8-5033H | Recombinant Human IRF8 Protein, GST-tagged | +Inquiry |
IRF8-4606M | Recombinant Mouse IRF8 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IRF8-5159HCL | Recombinant Human IRF8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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