Recombinant Mouse Itm2c Protein, Myc/DDK-tagged
Cat.No. : | Itm2c-3617M |
Product Overview : | Purified recombinant protein of mouse full-length integral membrane protein 2C (Itm2c), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 30.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Itm2c integral membrane protein 2C [ Mus musculus (house mouse) ] |
Official Symbol : | Itm2c |
Synonyms : | ITM2C; integral membrane protein 2C; transmembrane protein BRI3; integral membrane protein 3; E25; BRI3; E25C; ITM3; 3110038L02Rik |
Gene ID : | 64294 |
mRNA Refseq : | NM_022417 |
Protein Refseq : | NP_071862 |
UniProt ID : | Q91VK4 |
Products Types
◆ Recombinant Protein | ||
ITM2C-2777R | Recombinant Rat ITM2C Protein, His (Fc)-Avi-tagged | +Inquiry |
ITM2C-379C | Recombinant Cynomolgus Monkey ITM2C Protein, His (Fc)-Avi-tagged | +Inquiry |
ITM2C-4651M | Recombinant Mouse ITM2C Protein, His (Fc)-Avi-tagged | +Inquiry |
ITM2C-8383M | Recombinant Mouse ITM2C Protein | +Inquiry |
ITM2C-633C | Recombinant Cynomolgus ITM2C Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ITM2C-5115HCL | Recombinant Human ITM2C 293 Cell Lysate | +Inquiry |
ITM2C-5116HCL | Recombinant Human ITM2C 293 Cell Lysate | +Inquiry |
ITM2C-5114HCL | Recombinant Human ITM2C 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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