Recombinant Mouse Kitl Protein
Cat.No. : | Kitl-7284M |
Product Overview : | Recombinant Mouse Kitl Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins. |
Source : | E. coli |
Species : | Mouse |
Form : | Liquid |
Molecular Mass : | 18 kDa |
Protein length : | 26-189 |
AA Sequence : | MKEICGNPVTDNVKDITKLVANLPN DYMITLNYVAGMDVLPSHCWLRDMV IQLSLSLTTLLDKFSNISEGLSNYS IIDKLGKIVDDLVLCMEENAPKNIK ESPKRPETRSFTPEEFFSIFNRSID AFKDFMVASDTSDCVLSSTLGPEKD SRVSVTKPFMLPPVA |
Purity : | > 95 % by SDS-PAGE |
Stability : | Shelf life: one year from despatch. |
Storage : | Store undiluted at 2-8 centigrade for one week or (in aliquots) at -20 to -80 centigrade for longer. Avoid repeated freezing and thawing. |
Concentration : | 1.0 mg/mL (determined by Bradford assay) |
Storage Buffer : | Phosphate buffer saline (pH 7.4) containing 10 % glycerol |
Gene Name : | Kitl kit ligand [ Mus musculus (house mouse) ] |
Official Symbol : | Kitl |
Synonyms : | Kitl; kit ligand; S; Gb; SC; SF; Sl; bl; Clo; Con; Kit; Mgf; SCF; SLF; Ste; blz; Kitlg; contrasted; kit ligand; C-kit ligand; Steel factor; cloud gray; grizzle-belly; hematopoietic growth factor KL; mast cell growth factor; stem cell factor; EC 3.2.1.31 |
Gene ID : | 17311 |
mRNA Refseq : | NM_001347156 |
Protein Refseq : | NP_001334085 |
UniProt ID : | P20826 |
Products Types
◆ Recombinant Protein | ||
Kitlg-200R | Recombinant Rat Kitlg Protein | +Inquiry |
Kitlg-150K | Active Recombinant Rat Kitlg Protein (164 aa) | +Inquiry |
KITLG-152K | Active Recombinant Human KITLG Protein (165 aa) | +Inquiry |
KITLG-525H | Recombinant Human KITLG Protein | +Inquiry |
KITLG-057K | Active Recombinant Human KITLG Protein (165 aa) | +Inquiry |
◆ Lysates | ||
KITLG-583MCL | Recombinant Mouse KITLG cell lysate | +Inquiry |
KITLG-571HCL | Recombinant Human KITLG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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