Recombinant Mouse Klhl2 Protein, Myc/DDK-tagged

• Cat.No.: Klhl2-3713M
• Product Overview: Purified recombinant protein of mouse full-length kelch-like 2, Mayven (Klhl2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Promotes growth of cell projections in oligodendrocyte precursors. Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation. Plays a role in the reorganization of the actin cytoskeleton.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 66 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Klhl2 kelch-like 2, Mayven [ Mus musculus (house mouse) ]
• Official Symbol: Klhl2
• Synonyms: KLHL2; kelch-like 2, Mayven (Drosophila); kelch-like protein 2; Mav; AU020744; ABP-KELCH; mKIAA4249; 6030411N21Rik; KIAA4249
• Gene ID: 77113
• mRNA Refseq: NM_178633
• Protein Refseq: NP_848748
• UniProt ID: Q8JZP3