Recombinant Mouse Knstrn Protein, Myc/DDK-tagged
Cat.No. : | Knstrn-2437M |
Product Overview : | Purified recombinant protein of mouse full-length DNA segment, Chr 2, ERATO Doi 750, expressed (cDNA clone MGC:30961 IMAGE:4021550), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 26.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Knstrn kinetochore-localized astrin/SPAG5 binding [ Mus musculus (house mouse) ] |
Official Symbol : | Knstrn |
Synonyms : | Knstrn; kinetochore-localized astrin/SPAG5 binding; SKAP; C15orf23; Traf4af1; D2Ertd750; D2Ertd750e; 1700025D04Rik; small kinetochore-associated protein; TRAF4 associated factor 1 homolog; TRAF4-associated factor 1; kinastrin; kinetochore-localized astrin-binding protein; kinetochore-localized astrin/SPAG5-binding protein; putative TRAF4-associated factor 1 |
Gene ID : | 51944 |
mRNA Refseq : | NM_026412 |
Protein Refseq : | NP_080688 |
UniProt ID : | Q9D9Z1 |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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