Recombinant Mouse LILRB4 protein, Fc-tagged
Cat.No. : | LILRB4-316M |
Product Overview : | Recombinant Mouse LILRB4 protein (Gly24-Lys238), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
- Download
Description : | Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4/CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4/CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. |
Source : | HEK293 |
Species : | Mouse |
Tag : | human IgG1 Fc |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 50.7 kDa. As a result of glycosylation, the protein migrates as 60-66 kDa under reducing (R) condition, and 120-140 kDa under non-reducing (NR) condition (SDS-PAGE). |
Protein length : | 215 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | LILRB4 |
Official Symbol : | LILRB4 |
Synonyms : | HM18; ILT3; gp49; CD85K; Gp49b; LIR-5 |
Gene ID : | 14728 |
mRNA Refseq : | NM_013532.2 |
Protein Refseq : | NP_038560.1 |
UniProt ID : | Q64281 |
Products Types
◆ Recombinant Protein | ||
LILRB4-3358H | Recombinant Human LILRB4 Protein, His (Fc)-Avi-tagged | +Inquiry |
LILRB4-359C | Recombinant Cynomolgus monkey LILRB4 Protein, His-tagged | +Inquiry |
LILRB4-360H | Recombinant Human LILRB4 Protein, Fc-tagged | +Inquiry |
LILRB4-13H | Recombinant Human LILRB4 Protein, HIgG1 Fc-tagged | +Inquiry |
Lilrb4-361M | Recombinant Mouse Lilrb4 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
LILRB4-380HCL | Recombinant Human LILRB4 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All LILRB4 Products
Required fields are marked with *
My Review for All LILRB4 Products
Required fields are marked with *
0
Inquiry Basket