Recombinant Mouse Mertk Protein, hFc tagged, Biotinylated
Cat.No. : | Mertk-04M |
Product Overview : | Biotinylated Recombinant Mouse MerTK (C-hFc) is produced by Human Cells. The target gene encoding Glu23 - Phe498 is expressed with a C-hFc tag. |
- Specification
- Gene Information
- Related Products
Description : | Tyrosine-protein kinase Mer(MERTK) is a member of the TYRO3/AXL/MER (TAM) receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. |
Source : | Human Cells |
Species : | Mouse |
Tag : | hFc |
Protein Length : | Glu23 - Phe498 |
Endotoxin : | Less than 0.1 ng/μg (1 EU/μg) |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 |
Shipping : | Ambient |
Gene Name : | Mertk c-mer proto-oncogene tyrosine kinase [ Mus musculus (house mouse) ] |
Official Symbol : | Mertk |
Synonyms : | MERTK; Mer |
Gene ID : | 17289 |
mRNA Refseq : | NM_008587 |
Protein Refseq : | NP_032613 |
UniProt ID : | Q12866 |
Products Types
◆ Recombinant Protein | ||
Mertk-7397M | Active Recombinant Mouse Mertk protein(Glu573-Tyr867), His&GST-tagged | +Inquiry |
MERTK-3218H | Recombinant Human MERTK protein(Glu578-Tyr872) | +Inquiry |
MERTK-1352H | Recombinant Human MERTK protein(Glu578-Tyr872), His&GST-tagged | +Inquiry |
MERTK-950H | Recombinant Human MERTK Protein, MYC/DDK-tagged | +Inquiry |
Mertk-4035M | Recombinant Mouse Mertk Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
MERTK-1816MCL | Recombinant Mouse MERTK cell lysate | +Inquiry |
MERTK-001HCL | Recombinant Human MERTK cell lysate | +Inquiry |
MERTK-2888HCL | Recombinant Human MERTK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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