Recombinant Mouse Mgrn1 Protein, Myc/DDK-tagged
Cat.No. : | Mgrn1-4063M |
Product Overview : | Purified recombinant protein of mouse full-length mahogunin, ring finger 1 (Mgrn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin-protein ligase. Mediates TSG101 monoubiquitination at multiple sites. Plays a role in the regulation of endosome-to-lysosome trafficking. Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production. Does not inhibit ADRB2-signaling. Does not promote MC1R ubiquitination. Acts also as a negative regulator of hedgehog signaling. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 58.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Mgrn1 mahogunin, ring finger 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Mgrn1 |
Synonyms : | MGRN1; mahogunin, ring finger 1; E3 ubiquitin-protein ligase MGRN1; mahoganoid; mahogunin RING finger protein 1; probable E3 ubiquitin-protein ligase MGRN1; md; nc; mKIAA0544; 2610042J20Rik |
Gene ID : | 17237 |
mRNA Refseq : | NM_029657 |
Protein Refseq : | NP_083933 |
UniProt ID : | Q9D074 |
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◆ Lysates | ||
MGRN1-4328HCL | Recombinant Human MGRN1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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