Recombinant Mouse Nfe2 Protein, Myc/DDK-tagged

• Cat.No.: Nfe2-4391M
• Product Overview: Purified recombinant protein of mouse full-length nuclear factor, erythroid derived 2 (Nfe2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 42 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nfe2 nuclear factor, erythroid derived 2 [ Mus musculus (house mouse) ]
• Official Symbol: Nfe2
• Synonyms: NFE2; nuclear factor, erythroid derived 2; transcription factor NF-E2 45 kDa subunit; p45 NF-E2; leucine zipper protein NF-E2; nuclear factor, erythroid derived 2, 45 kDa; nuclear factor, erythroid-derived 2 45 kDa subunit; p45; 45kDa; NF-E2; p45NFE2; p45nf-e2
• Gene ID: 18022
• mRNA Refseq: NM_008685
• Protein Refseq: NP_032711
• UniProt ID: Q07279