Recombinant Mouse NOTUM Protein Pre-coupled Magnetic Beads

• Cat.No.: NOTUM-6142M-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Mouse
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Notum notum pectinacetylesterase homolog (Drosophila) [ Mus musculus (house mouse) ]
• Official Symbol: NOTUM
• Synonyms: NOTUM; notum pectinacetylesterase homolog (Drosophila); protein notum homolog
• Gene ID: 77583
• mRNA Refseq: NM_175263.4
• Protein Refseq: NP_780472.3
• UniProt ID: Q8R116

Reviews

08/26/2021

Its excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.

11/09/2020

Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.

07/20/2020

Its usage in ELISA and protein electron microscopy structure analysis has been reported to yield highly reproducible and interpretable results, providing valuable insights into the molecular mechanisms and biological processes under investigation.

Q&As

In neurological disorders, how does NOTUM protein contribute to therapeutic interventions?

NOTUM's role in Wnt signaling modulation has implications for neurodegenerative disorders, and targeting NOTUM may offer therapeutic avenues for conditions such as Alzheimer's disease.

How does NOTUM protein affect stem cell function?

NOTUM is involved in the regulation of stem cell behavior through its influence on Wnt signaling, making it a target for manipulating stem cell activities.

Are there any ongoing clinical trials exploring NOTUM-targeted therapies?

Several clinical trials are underway to investigate the safety and efficacy of NOTUM inhibitors in cancer patients, providing valuable insights into their clinical potential.

How does NOTUM protein influence tissue homeostasis?

NOTUM's role in regulating Wnt signaling contributes to tissue homeostasis, and understanding this mechanism can provide insights into maintaining tissue health.

How can NOTUM protein be utilized in personalized medicine approaches?

Understanding individual variations in NOTUM expression and activity may allow for personalized treatment strategies, tailoring interventions based on a patient's molecular profile.