Recombinant Mouse Nprl3 Protein, Myc/DDK-tagged
Cat.No. : | Nprl3-4478M |
Product Overview : | Purified recombinant protein of mouse full-length nitrogen permease regulator-like 3 (Nprl3), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 63.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Nprl3 nitrogen permease regulator-like 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Nprl3 |
Synonyms : | Nprl3; nitrogen permease regulator-like 3; Ma; Ph; Pr; Aag; Phg; HS-2; HS-4; Mare; HS-26; HS-40; Prox1; m(alp; CGTHBA; m(alpha)RE; GATOR complex protein NPRL3; -14; alpha globin regulatory element containing; alpha-globin regulatory element-containing gene protein; nitrogen permease regulator 3-like protein; proximal locus to the hemoglobin alpha chain complex |
Gene ID : | 17168 |
mRNA Refseq : | NM_181569 |
Protein Refseq : | NP_853547 |
UniProt ID : | Q8VIJ8 |
Products Types
◆ Recombinant Protein | ||
NPRL3-3668H | Recombinant Human NPRL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NPRL3-497H | Recombinant Human NPRL3 | +Inquiry |
NPRL3-3149Z | Recombinant Zebrafish NPRL3 | +Inquiry |
NPRL3-3667H | Recombinant Human NPRL3 protein, His-tagged | +Inquiry |
◆ Lysates | ||
NPRL3-3730HCL | Recombinant Human NPRL3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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