Recombinant Mouse Pah protein(2-453aa), His-tagged

• Cat.No.: Pah-459M
• Product Overview: Recombinant Mouse Pah protein(P16331)(2-453aa), fused with N-terminal His tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Mouse
• Tag: N-His
• Protein length: 2-453aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 55.9 kDa
• AASequence: AAVVLENGVLSRKLSDFGQETSYIE DNSNQNGAVSLIFSLKEEVGALAKV LRLFEENEINLTHIESRPSRLNKDE YEFFTYLDKRSKPVLGSIIKSLRND IGATVHELSRDKEKNTVPWFPRTIQ ELDRFANQILSYGAELDADHPGFKD PVYRARRKQFADIAYNYRHGQPIPR VEYTEEERKTWGTVFRTLKALYKTH ACYEHNHIFPLLEKYCGFREDNIPQ LEDVSQFLQTCTGFRLRPVAGLLSS RDFLGGLAFRVFHCTQYIRHGSKPM YTPEPDICHELLGHVPLFSDRSFAQ FSQEIGLASLGAPDEYIEKLATIYW FTVEFGLCKEGDSIKAYGAGLLSSF GELQYCLSDKPKLLPLELEKTACQE YTVTEFQPLYYVAESFNDAKEKVRT FAATIPRPFSVRYDPYTQRVEVLDN TQQLKILADSINSEVGILCHALQKI KS
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: Pah phenylalanine hydroxylase [ Mus musculus ]
• Official Symbol: Pah
• Synonyms: PAH; phenylalanine hydroxylase; phenylalanine-4-hydroxylase; phe-4-monooxygenase; AW106920
• Gene ID: 18478
• mRNA Refseq: NM_008777
• Protein Refseq: NP_032803

Reviews

06/20/2022

I highly recommend the use of the PAH protein in various experimental applications.

03/23/2022

Considering its outstanding performance across multiple assays, I confidently endorse the inclusion of the PAH protein in diverse research studies.

12/27/2021

the PAH protein has been successfully utilized in protein electron microscopy structure analysis, providing valuable insights into molecular structures and interactions.

Q&As

Can PAH be treated with medications?

Yes, several medications are available to manage the symptoms and slow the progression of PAH.

How can a better understanding of PAH proteins benefit patients with PAH?

Understanding the role of proteins in PAH can lead to the development of more targeted and effective treatments, improving the quality of life for patients with PAH.

Are there specific biomarkers related to PAH that involve protein expression?

Yes, certain biomarkers, such as brain natriuretic peptide (BNP) and endothelin-1, can be indicative of PAH.

Are there any protein-targeted therapies for PAH?

Research is ongoing in the development of protein-targeted therapies for PAH, but no specific protein-targeted drugs are widely used as of my last update in January 2022.

How can proteins be used in the diagnosis and prognosis of PAH?

Protein biomarkers can help in early diagnosis, and monitoring their levels can aid in assessing disease progression and response to treatment.