Recombinant Mouse Poc1b Protein, Myc/DDK-tagged

• Cat.No.: Poc1b-4974M
• Product Overview: Purified recombinant protein of mouse full-length POC1 centriolar protein B (Poc1b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation. Required for retinal integrity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 53.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Poc1b POC1 centriolar protein B [ Mus musculus (house mouse) ]
• Official Symbol: Poc1b
• Synonyms: POC1B; POC1 centriolar protein homolog B (Chlamydomonas); POC1 centriolar protein homolog B; WD repeat domain 51B; WD repeat-containing protein 51B; Wdr51b; 4933430F16Rik
• Gene ID: 382406
• mRNA Refseq: NM_027740
• Protein Refseq: NP_082016
• UniProt ID: Q8BHD1