Recombinant Mouse Polr3k Protein, Myc/DDK-tagged
Cat.No. : | Polr3k-5009M |
Product Overview : | Purified recombinant protein of mouse full-length polymerase (RNA) III (DNA directed) polypeptide K (Polr3k), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 12.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Polr3k polymerase (RNA) III (DNA directed) polypeptide K [ Mus musculus (house mouse) ] |
Official Symbol : | Polr3k |
Synonyms : | POLR3K; polymerase (RNA) III (DNA directed) polypeptide K; DNA-directed RNA polymerase III subunit RPC10; RNA polymerase III subunit C10; RNA polymerase III subunit C11; DNA-directed RNA polymerase III subunit K; C11; RPC10; RPC11; 12.3kDa; AI196849; AU014893; 1500004O14Rik |
Gene ID : | 67005 |
mRNA Refseq : | NM_025901 |
Protein Refseq : | NP_080177 |
UniProt ID : | Q9CQZ7 |
Products Types
◆ Recombinant Protein | ||
POLR3K-1852H | Recombinant Human POLR3K, GST-tagged | +Inquiry |
POLR3K-266H | Recombinant Human POLR3K, His-tagged | +Inquiry |
POLR3K-3355H | Recombinant Human POLR3K protein, His-SUMO-tagged | +Inquiry |
POLR3K-674Z | Recombinant Zebrafish POLR3K | +Inquiry |
◆ Lysates | ||
POLR3K-3020HCL | Recombinant Human POLR3K 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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