Recombinant Mouse Ppm1d Protein, Myc/DDK-tagged
Cat.No. : | Ppm1d-5046M |
Product Overview : | Purified recombinant protein of mouse full-length protein phosphatase 1D magnesium-dependent, delta isoform (cDNA clone MGC:32306 IMAGE:5026376), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Involved in the negative regulation of p53 expression. Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation. Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 74.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ppm1d protein phosphatase 1D magnesium-dependent, delta isoform [ Mus musculus (house mouse) ] |
Official Symbol : | Ppm1d |
Synonyms : | Ppm1d; protein phosphatase 1D magnesium-dependent, delta isoform; Wi; Wip1; AV338790; protein phosphatase 1D; PP2C-delta; p53-induced protein phosphatase 1; protein phosphatase magnesium-dependent 1 delta; EC 3.1.3.16 |
Gene ID : | 53892 |
mRNA Refseq : | NM_016910 |
Protein Refseq : | NP_058606 |
UniProt ID : | Q9QZ67 |
Products Types
◆ Recombinant Protein | ||
PPM1D-1744H | Recombinant Human PPM1D Protein, His (Fc)-Avi-tagged | +Inquiry |
PPM1D-2668H | Recombinant Human PPM1D Protein, MYC/DDK-tagged | +Inquiry |
PPM1D-3371R | Recombinant Rhesus Macaque PPM1D Protein, His (Fc)-Avi-tagged | +Inquiry |
PPM1D-3553R | Recombinant Rhesus monkey PPM1D Protein, His-tagged | +Inquiry |
PPM1D-2917H | Recombinant Human PPM1D protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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