Recombinant Mouse Ppm1g Protein, Myc/DDK-tagged

• Cat.No.: Ppm1g-5048M
• Product Overview: Purified recombinant protein of mouse full-length protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (Ppm1g), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: May be involved in regulation of cell cycle.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 58.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform [ Mus musculus (house mouse) ]
• Official Symbol: Ppm1g
• Synonyms: PPM1G; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 1G; PP2C-gamma; protein phosphatase 1C; protein phosphatase 2C isoform gamma; fibroblast growth factor inducible 13; fibroblast growth factor-inducible protein 13; protein phosphatase magnesium-dependent 1 gamma; Fin13; AI385652
• Gene ID: 14208
• mRNA Refseq: NM_008014
• Protein Refseq: NP_032040
• UniProt ID: Q61074

Reviews

11/14/2022

PPM1G protein's utility in protein electron microscopy structure analysis is commendable.

12/03/2019

It enables researchers to delve deeper into the intricacies of protein behavior and aids in advancing our knowledge in various fields, such as molecular biology, biochemistry, and structural biology.

11/11/2019

It demonstrates excellent performance in ELISA assays, making it an ideal choice for researchers studying protein-protein interactions, antibody detection, or biomarker identification.

Q&As

Can PPM1G be targeted for cancer treatment?

Research is ongoing to explore the therapeutic potential of targeting PPM1G in cancer. Inhibiting or modulating its activity may be a strategy for cancer therapy.

Are there any known associations between PPM1G and cancer?

Yes, abnormal expression of PPM1G has been linked to certain cancers, suggesting its potential role as a biomarker or therapeutic target.

Are there any genetic disorders associated with PPM1G mutations?

While rare, mutations in the PPM1G gene have been reported and may be associated with certain genetic disorders. Further research is needed to understand the implications.

How does PPM1G contribute to DNA repair mechanisms?

PPM1G is involved in the regulation of DNA repair processes, influencing the repair of damaged DNA and maintaining genomic stability.

Can PPM1G be used as a diagnostic marker for specific diseases?

PPM1G expression levels may serve as a diagnostic marker for certain diseases, including some cancers, but more studies are required to establish its diagnostic utility.