Recombinant Mouse Ptgr1 Protein, Myc/DDK-tagged
Cat.No. : | Ptgr1-5223M |
Product Overview : | Purified recombinant protein of mouse full-length prostaglandin reductase 1 (Ptgr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | NAD(P)H-dependent oxidoreductase involved in metabolic inactivation of pro- and anti-inflammatory eicosanoids: prostaglandins (PG), leukotrienes (LT) and lipoxins (LX). Catalyzes with high efficiency the reduction of the 13,14 double bond of 15-oxoPGs, including 15-oxo-PGE1, 15-oxo-PGE2, 15-oxo-PGF1-alpha and 15-oxo-PGF2-alpha. Catalyzes with lower efficiency the oxidation of the hydroxyl group at C12 of LTB4 and its derivatives, converting them into biologically less active 12-oxo-LTB4 metabolites. Reduces 15-oxo-LXA4 to 13,14 dihydro-15-oxo-LXA4, enhancing neutrophil recruitment at the inflammatory site. Plays a role in metabolic detoxification of alkenals and ketones. Reduces alpha,beta-unsaturated alkenals and ketones, particularly those with medium-chain length, showing highest affinity toward (2E)-decenal and (3E)-3-nonen-2-one. May inactivate 4-hydroxy-2-nonenal, a cytotoxic lipid constituent of oxidized low-density lipoprotein particles. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 35.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ptgr1 prostaglandin reductase 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Ptgr1 |
Synonyms : | PTGR1; prostaglandin reductase 1; PRG-1; 15-oxoprostaglandin 13-reductase; leukotriene B4 12-hydroxydehydrogenase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; Ltb4dh; 2510002C21Rik |
Gene ID : | 67103 |
mRNA Refseq : | NM_025968 |
Protein Refseq : | NP_080244 |
UniProt ID : | Q91YR9 |
Products Types
◆ Recombinant Protein | ||
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PTGR1-1794H | Recombinant Human PTGR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTGR1-3084C | Recombinant Chicken PTGR1 | +Inquiry |
PTGR1-1936Z | Recombinant Zebrafish PTGR1 | +Inquiry |
◆ Lysates | ||
PTGR1-2708HCL | Recombinant Human PTGR1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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