Recombinant Mouse Ranbp9 Protein, Myc/DDK-tagged
Cat.No. : | Ranbp9-5369M |
Product Overview : | Purified recombinant protein of mouse full-length RAN binding protein 9 (Ranbp9), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways. Acts as a mediator of cell spreading and actin cytoskeleton rearrangement. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 76.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ranbp9 RAN binding protein 9 [ Mus musculus (house mouse) ] |
Official Symbol : | Ranbp9 |
Synonyms : | RANBP9; RAN binding protein 9; ran-binding protein 9; ran-binding protein M; B cell antigen receptor Ig beta associated protein 1; B-cell antigen receptor Ig beta-associated protein 1; Ibap1; IBAP-1; RanBPM |
Gene ID : | 56705 |
mRNA Refseq : | NM_019930 |
Protein Refseq : | NP_064314 |
UniProt ID : | P69566 |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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