Recombinant Mouse Rbm4 Protein, Myc/DDK-tagged
Cat.No. : | Rbm4-5413M |
Product Overview : | Purified recombinant protein of mouse full-length RNA binding motif protein 4 (Rbm4), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 40 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rbm4 RNA binding motif protein 4 [ Mus musculus (house mouse) ] |
Official Symbol : | Rbm4 |
Synonyms : | RBM4; RNA binding motif protein 4; RNA-binding protein 4; lark homolog; RNA-binding motif protein 4; RNA-binding motif protein 4a; lark; Lark1; Mlark; Rbm4a; 4921506I22Rik |
Gene ID : | 19653 |
mRNA Refseq : | NM_009032 |
Protein Refseq : | NP_033058 |
UniProt ID : | Q8C7Q4 |
Products Types
◆ Recombinant Protein | ||
RBM4-590C | Recombinant Cynomolgus Monkey RBM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
RBM4-655H | Recombinant Human RBM4 Protein, MYC/DDK-tagged | +Inquiry |
RBM4-847C | Recombinant Cynomolgus RBM4 Protein, His-tagged | +Inquiry |
RBM4-105H | Recombinant Human RBM4, GST-tagged | +Inquiry |
RBM4-31230TH | Recombinant Human RBM4, His-tagged | +Inquiry |
◆ Lysates | ||
RBM4-531HCL | Recombinant Human RBM4 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All Rbm4 Products
Required fields are marked with *
My Review for All Rbm4 Products
Required fields are marked with *
0
Inquiry Basket