Recombinant Mouse Rcn3 Protein, Myc/DDK-tagged

• Cat.No.: Rcn3-5439M
• Product Overview: Purified recombinant protein of mouse full-length reticulocalbin 3, EF-hand calcium binding domain (Rcn3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum. Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens. This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 38 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rcn3 reticulocalbin 3, EF-hand calcium binding domain [ Mus musculus (house mouse) ]
• Official Symbol: Rcn3
• Synonyms: RCN3; reticulocalbin 3, EF-hand calcium binding domain; reticulocalbin-3; RLP49; D7Ertd671e; 6030455P07Rik; D530026G20Rik; MGC102610
• Gene ID: 52377
• mRNA Refseq: NM_026555
• Protein Refseq: NP_080831
• UniProt ID: Q8BH97