Recombinant Mouse Rgs2 Protein, Myc/DDK-tagged

• Cat.No.: Rgs2-5496M
• Product Overview: Purified recombinant protein of mouse full-length regulator of G-protein signaling 2 (Rgs2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. It is involved in the negative regulation of the angiotensin-activated signaling pathway. Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 24.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rgs2 regulator of G-protein signaling 2 [ Mus musculus (house mouse) ]
• Official Symbol: Rgs2
• Synonyms: RGS2; regulator of G-protein signaling 2; GOS8
• Gene ID: 19735
• mRNA Refseq: NM_009061
• Protein Refseq: NP_033087
• UniProt ID: O08849