Recombinant Mouse Rnaset2a Protein, MYC/DDK-tagged
Cat.No. : | Rnaset2a-007M |
Product Overview : | Purified recombinant protein of full-length mouse ribonuclease T2A (Rnaset2a), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | Ribonuclease that plays an essential role in innate immune response by recognizing and degrading RNAs from microbial pathogens that are subsequently sensed by TLR8. Cleaves preferentially single-stranded RNA molecules between purine and uridine residues, which critically contributes to the supply of catabolic uridine and the generation of purine-2',3'-cyclophosphate-terminated oligoribonucleotides. In turn, RNase T2 degradation products promote the RNA-dependent activation of TLR8. Plays also a key role in degradation of mitochondrial RNA and processing of non-coding RNA imported from the cytosol into mitochondria. Participates as well in degradation of mitochondrion-associated cytosolic rRNAs. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 30.1 kDa |
Purity : | >80%, as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rnaset2a ribonuclease T2A [ Mus musculus (house mouse) ] |
Official Symbol : | Rnaset2a |
Synonyms : | Rnaset2a; ribonuclease T2A; C79750; Rnaset2; RNASE6PL; 0610007O07Rik; 4833423A10Rik; 4930532K22Rik; ribonuclease T2-A; ribonuclease 6; ribonuclease 6-A; ribonuclease T2; EC 4.6.1.19 |
Gene ID : | 100037283 |
mRNA Refseq : | NM_001083938 |
Protein Refseq : | NP_001077407 |
UniProt ID : | Q5FWA0 |
Products Types
◆ Recombinant Protein | ||
Rnaset2a-2023M | Recombinant Mouse Rnaset2a Protein, His-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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