Recombinant Mouse Rnf185 Protein, Myc/DDK-tagged
Cat.No. : | Rnf185-5553M |
Product Overview : | Purified recombinant protein of mouse full-length ring finger protein 185 (cDNA clone MGC:19394 IMAGE:3153870), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 20.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rnf185 ring finger protein 185 [ Mus musculus (house mouse) ] |
Official Symbol : | Rnf185 |
Synonyms : | Rnf185; ring finger protein 185; E3 ubiquitin-protein ligase RNF185; RING-type E3 ubiquitin transferase RNF185; EC 2.3.2.27 |
Gene ID : | 193670 |
mRNA Refseq : | NM_145355 |
Protein Refseq : | NP_663330 |
UniProt ID : | Q91YT2 |
Products Types
◆ Recombinant Protein | ||
RNF185-4737R | Recombinant Rat RNF185 Protein, His (Fc)-Avi-tagged | +Inquiry |
RNF185-7669M | Recombinant Mouse RNF185 Protein, His (Fc)-Avi-tagged | +Inquiry |
RNF185-676H | Recombinant Human RNF185 Protein, MYC/DDK-tagged | +Inquiry |
RNF185-14325M | Recombinant Mouse RNF185 Protein | +Inquiry |
RNF185-5078R | Recombinant Rat RNF185 Protein | +Inquiry |
◆ Lysates | ||
RNF185-1523HCL | Recombinant Human RNF185 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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