Recombinant Mouse Sco1 Protein, Myc/DDK-tagged

• Cat.No.: Sco1-5718M
• Product Overview: Purified recombinant protein of mouse full-length SCO1 cytochrome c oxidase assembly protein (Sco1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 31.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sco1 SCO1 cytochrome c oxidase assembly protein [ Mus musculus (house mouse) ]
• Official Symbol: Sco1
• Synonyms: SCO1; SCO cytochrome oxidase deficient homolog 1 (yeast); protein SCO1 homolog, mitochondrial; D11Bwg1310e; 2610001C07Rik
• Gene ID: 52892
• mRNA Refseq: NM_001040026
• Protein Refseq: NP_001035115
• UniProt ID: Q5SUC9