Recombinant Mouse Sh2b3 Protein, MYC/DDK-tagged
Cat.No. : | Sh2b3-1332M |
Product Overview : | Purified recombinant protein of full-length mouse SH2B adaptor protein 3 (Sh2b3), with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the SH2B family of adapter proteins that play an important role in T cell receptor signaling. This gene is preferentially expressed in hematopoietic stem cells, hematopoietic progenitors, pre and immature B cells, as well as megakaryocytes and mastocytes. In hematopoietic stem cells, the encoded protein is a key regulator of self-renewal, proliferation and apoptosis. Mice lacking the encoded protein exhibit pre and immature B cell expansion in spleen and the bone marrow. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 60.9 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Sh2b3 SH2B adaptor protein 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Sh2b3 |
Synonyms : | Sh2b3; SH2B adaptor protein 3; Lnk; AI429800; SH2B adapter protein 3; linker of T-cell receptor pathways; lymphocyte-specific adapter protein Lnk; signal transduction protein Lnk |
Gene ID : | 16923 |
mRNA Refseq : | NM_008507 |
Protein Refseq : | NP_032533 |
UniProt ID : | O09039 |
Products Types
◆ Recombinant Protein | ||
SH2B3-8115M | Recombinant Mouse SH2B3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SH2B3-5032R | Recombinant Rat SH2B3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SH2B3-2000H | Recombinant Human SH2B3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SH2B3-054H | Recombinant Human SH2B3 Mutant (R262W) Protein, DDK/His-tagged | +Inquiry |
SH2B3-051H | Recombinant Human SH2B3 Mutant (R262W) Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
SH2B3-1880HCL | Recombinant Human SH2B3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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