Recombinant Mouse Sigirr
Cat.No. : | Sigirr-501M |
- Specification
- Gene Information
- Related Products
Cat. No. : | Sigirr-501M |
Description : | Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family. It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling. It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium. |
Source : | Mammalian cells |
Molecular Weight : | The predicted molecular weight of Recombinant Mouse SIGIRR is Mr 39 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 63 kDa. |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <0.1 ng per 1 µg as determined by the LAL method. |
Storage And Stability : | The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Gene Name : | Sigirr single immunoglobulin and toll-interleukin 1 receptor (TIR) domain [ Mus musculus ] |
Synonyms : | Sigirr; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; TIR8; AI256711; MGC102426; single Ig IL-1 receptor related protein; single Ig IL-1R-related protein |
Gene ID : | 24058 |
mRNA Refseq : | NM_023059 |
Protein Refseq : | NP_075546 |
UniProt ID : | Q9JLZ8 |
Chromosome Location : | 7 F5 |
Function : | receptor activity; transmembrane receptor activity |
Products Types
◆ Recombinant Protein | ||
Sigirr-5875M | Recombinant Mouse Sigirr Protein, Myc/DDK-tagged | +Inquiry |
SIGIRR-2054M | Recombinant Mouse SIGIRR Protein (1-117 aa), His-tagged | +Inquiry |
SIGIRR-4483H | Recombinant Human SIGIRR Protein, His (Fc)-Avi-tagged | +Inquiry |
Sigirr-10614M | Recombinant Mouse Sigirr Protein, His (Fc)-Avi-tagged | +Inquiry |
SIGIRR-5059R | Recombinant Rat SIGIRR Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SIGIRR-1091HCL | Recombinant Human SIGIRR cell lysate | +Inquiry |
SIGIRR-2773MCL | Recombinant Mouse SIGIRR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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