Recombinant Mouse Smug1 Protein, Myc/DDK-tagged
Cat.No. : | Smug1-5983M |
Product Overview : | Purified recombinant protein of mouse full-length single-strand selective monofunctional uracil DNA glycosylase (Smug1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 30.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Smug1 single-strand selective monofunctional uracil DNA glycosylase [ Mus musculus (house mouse) ] |
Official Symbol : | Smug1 |
Synonyms : | SMUG1; single-strand selective monofunctional uracil DNA glycosylase; C85220; 1200013B09Rik; A930006H09Rik |
Gene ID : | 71726 |
mRNA Refseq : | NM_027885 |
Protein Refseq : | NP_082161 |
UniProt ID : | Q6P5C5 |
Products Types
◆ Recombinant Protein | ||
SMUG1-8504M | Recombinant Mouse SMUG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMUG1-5288R | Recombinant Rat SMUG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMUG1-4168R | Recombinant Rhesus Macaque SMUG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMUG1-15652M | Recombinant Mouse SMUG1 Protein | +Inquiry |
SMUG1-2826H | Recombinant Human SMUG1, GST-tagged | +Inquiry |
◆ Lysates | ||
SMUG1-1648HCL | Recombinant Human SMUG1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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