Recombinant Mouse Sod1 protein, His-tagged

• Cat.No.: Sod1-5524M
• Product Overview: Recombinant Mouse Sod1 protein(P08228)(2-154aa), fused to N-terminal His tag, was expressed in Yeast.

Specification

• Source: Yeast
• Species: Mouse
• Tag: His
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 17.8 kDa
• Protein length: 2-154aa
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.

Gene Information

• Gene Name: Sod1 superoxide dismutase 1, soluble [ Mus musculus ]
• Official Symbol: Sod1
• Synonyms: SOD1; superoxide dismutase 1, soluble; superoxide dismutase [Cu-Zn]; Cu(2+)-Zn2+ superoxide dismutase; Ipo1; SODC; Ipo-1; Sod-1; CuZnSOD; Cu/Zn-SOD; B430204E11Rik; MGC107553
• Gene ID: 20655
• mRNA Refseq: NM_011434
• Protein Refseq: NP_035564

Reviews

11/15/2022

Worked perfectly, no problems.

10/09/2020

Quick delivery, fantastic product.

10/02/2020

Reliable results every time.

Q&As

Are there potential therapeutic strategies targeting SOD1 for disease treatment?

Therapeutic strategies may involve modulating SOD1 activity or expression to mitigate oxidative stress-related damage.

What is the primary biological function of SOD1 in cells?

SOD1 acts as an antioxidant, converting superoxide radicals to hydrogen peroxide and oxygen.

What are the genetic implications of mutations in the SOD1 gene?

Mutations in SOD1 can result in loss or gain of function, contributing to disease development.

How is SOD1 implicated in neurodegenerative diseases?

SOD1 mutations are implicated in Amyotrophic Lateral Sclerosis (ALS), leading to neurodegeneration.

In which cellular compartments is SOD1 primarily located?

SOD1 is primarily located in the cytoplasm and mitochondrial intermembrane space.

What role does SOD1 play in maintaining cellular redox balance?

It helps maintain cellular redox balance, protecting cells from oxidative damage.

How does SOD1 contribute to the cellular antioxidant defense system?

It plays a crucial role in cellular defense against oxidative stress.