Recombinant Mouse Sox17 Protein, Myc/DDK-tagged

• Cat.No.: Sox17-6052M
• Product Overview: Purified recombinant protein of mouse full-length SRY (sex determining region Y)-box 17 (Sox17), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the Sox (Sry-related high mobility group box) family of transcription factors involved in the regulation of embryonic development. The encoded protein plays a role in the determination of cell fate and in maintaining cell identity. This gene regulates tumor angiogenesis and tumor progression. Mutations in the human gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 45.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sox17 SRY (sex determining region Y)-box 17 [ Mus musculus (house mouse) ]
• Official Symbol: Sox17
• Synonyms: Sox17; SRY (sex determining region Y)-box 17; transcription factor SOX-17; SRY-box containing gene 17
• Gene ID: 20671
• mRNA Refseq: NM_011441
• Protein Refseq: NP_035571
• UniProt ID: Q61473