Recombinant Mouse Sparc Protein, Myc/DDK-tagged
Cat.No. : | Sparc-6073M |
Product Overview : | Purified recombinant protein of mouse full-length secreted acidic cysteine rich glycoprotein (Sparc), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 34.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Sparc secreted acidic cysteine rich glycoprotein [ Mus musculus (house mouse) ] |
Official Symbol : | Sparc |
Synonyms : | Sparc; secreted acidic cysteine rich glycoprotein; ON; BM-40; osteo; SPARC; basement-membrane protein 40; osteonectin; secreted protein acidic and rich in cysteine |
Gene ID : | 20692 |
mRNA Refseq : | NM_009242 |
Protein Refseq : | NP_033268 |
UniProt ID : | P07214 |
Products Types
◆ Recombinant Protein | ||
SPARC-001H | Recombinant Human SPARC Protein, MBP-tagged | +Inquiry |
Sparc-034M | Recombinant Mouse Sparc Protein, His-tagged | +Inquiry |
SPARC-2503H | Recombinant Human SPARC Protein, MYC/DDK-tagged | +Inquiry |
SPARC-4111H | Recombinant Human SPARC Protein, His (Fc)-Avi-tagged | +Inquiry |
SPARC-2725H | Recombinant Human SPARC Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
SPARC-287B | Native Bovine Osteonectin | +Inquiry |
SPARC-30653TH | Native Human SPARC | +Inquiry |
◆ Lysates | ||
SPARC-2616HCL | Recombinant Human SPARC cell lysate | +Inquiry |
SPARC-2120MCL | Recombinant Mouse SPARC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionSPARC is associated with cancer progression, as it can influence tumor growth, invasion, and angiogenesis. Its expression levels in tumors are often studied for prognostic and diagnostic purposes.
Yes, SPARC is being explored as a therapeutic target for cancer. Researchers are investigating ways to modulate its activity to hinder tumor progression or enhance the efficacy of existing treatments.
SPARC expression can be detected through techniques like immunohistochemistry, Western blotting, and molecular assays. These methods help assess SPARC levels in tissues or blood samples.
SPARC plays a role in tissue repair by influencing cell-matrix interactions and modulating the extracellular environment. Its involvement in wound healing and tissue regeneration makes it a subject of interest in regenerative medicine.
Yes, there are clinical trials exploring the potential of targeting SPARC in various diseases, including cancer. These trials aim to evaluate the safety and efficacy of SPARC-modulating agents.
Customer Reviews (3)
Write a reviewThe SPARC protein finds great utility in protein electron microscopy structure analysis, consistently delivering exceptional results.
Its remarkable sensitivity and specificity make it a valuable tool for accurate and robust data analysis, bolstering the credibility of research outcomes.
Notably, it exhibits exceptional performance in ELISA assays, providing reliable and precise results in the detection and quantification of target molecules.
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